Fall Stakeholder Meetings 2023
The Department of Energy Isotope Program (DOE IP) invites you to join us for virtual "one-on-one" stakeholder meetings on Oct. 19, Oct. 24 and Oct. 26, 2023. 
The Department of Energy Isotope Program will host three medical isotope virtual seminars focused on the following emerging alpha and beta emitters: astatine-211, lead-203/212, and cerium-134.
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DOE Isotope Program Highlights

Image courtesy of Brookhaven National Laboratory Depiction of a titanium-44/scandium-44 generator. The generator consists of a hydroxamate-based resin undergoing scandium-44 elution with hydrochloric acid.

Scientists Identify an Alternative System for Producing the Medical Isotope Scandium-44

An easy-to-use system can increase the availability of PET imaging agents to more patients.
Image courtesy of Jonathan Engle, University of Wisconsin. Summary of the production process for radioisotopes of scandium using recyclable, enriched calcium.

Researchers Improve Production for Short-Lived Scandium Radioisotopes

Hard to produce in quantities and purities appropriate for human use, scandium radioisotopes have potential for imaging cancer.
The binding of At-211 with mono- and diketones with different bond strengths. Image courtesy of Jon Burns, University of Alabama at Birmingham

Tunable Bonds: A Step Towards Targeted At-211 Cancer Therapy

Scientists can tune the strength of astatine-211 bonds with chemicals called ketones, laying the groundwork for a new class of radiopharmaceuticals.
Image courtesy of Brown, M.A., Metal Oxide Sorbents for the Separation of Radium and Actinium, Industrial & Engineering Chemistry Research, 59, 20472-20477 (2020). [DOI: 10.1021/acs.iecr.0c04084] The separation of radium and actinium is a major component in the production, distribution, and purity of targeted alpha therapy isotopes. This image shows the separation profiles of radium (purple) and actinium (green) across a zirconia resin.

Scientists Develop Inorganic Resins for Generating and Purifying Radium and Actinium

Research advances the chemistry and improves the purity of isotopes for targeted alpha therapy used in the treatment of cancers.