We're hiring!
The Department of Energy Office of Science is filling a position for the Isotope R&D and Production Office. The position will function as a program manager for Accelerator Isotope Facilities.
Cathy Sue Cutler named President of SNMMI
Cathy Sue Cutler, PhD, FSNMMI, Chair of the Isotope Research and Production Department at Brookhaven National Laboratory, has been appointed as the president of the Society of Nuclear Medicine and Molecular Imaging.
Brookhaven National Laboratory AP Hot Cells
The American Council of Engineering Companies of New York recently recognized the upgrades to the AP Hot Cells at BNL with a Platinum Award in the Studies & Research Category at the 2024 Engineering Excellence Awards Gala in New York City.

DOE Isotope Program Highlights

Illustration by Christopher Orosco, Oak Ridge National Laboratory Illustration of the structure of the radium compound characterized in this research. Single crystal X-ray diffraction provided detailed information on the bonding of radium in an organic molecule for the first time.

A First Look Inside Radium’s Solid-State Chemistry

Researchers used single crystal X-ray diffraction to learn about the structure and bonding of a highly radioactive radium compound.
Image courtesy of Bobba, K.N., et al., Evaluation of cerium/lanthanum-134 as a PET imaging theranostic pair for 225Ac alpha radiotherapeutics. Journal of Nuclear Medicine 64, 7 (2023). Radiopharmaceuticals based on cerium/lanthanum-134 have promise for prostate cancer imaging and therapy. At right, tumors show high tumor uptake of cerium-134. At left, a comparison of cerium-134 and actinium-225 shows a similar pattern of uptake in most tissues (note the tumor tissue on the leg).

Transforming Cancer Diagnosis and Treatment with Cerium/Lanthanum-134

Researchers advance the use of cerium/lanthanum-134 for medical scans in actinium-225 cancer therapy.
Image courtesy of Brookhaven National Laboratory Depiction of a titanium-44/scandium-44 generator. The generator consists of a hydroxamate-based resin undergoing scandium-44 elution with hydrochloric acid.

Scientists Identify an Alternative System for Producing the Medical Isotope Scandium-44

An easy-to-use system can increase the availability of PET imaging agents to more patients.
This image depicts a binding molecule delivering radium-223 to a cancer cell. Image courtesy of Adam Malin, Oak Ridge National Laboratory.

Capturing the Chemistry of Radium-223 for Cancer Treatment

Until now, there have been few efforts to get information on how radium binds with known chelators.